绿色荧光 CAG-LSL-GFP
描述:CAG-LSL-GFP小鼠在全身表达的CAG启动子后连接了一个带有LoxP-STOP-LoxP(LSL)序列的GFP基因。Cre重组酶移除STOP序列后,GFP基因被激活。用途:用于报告Cre重组酶活性,通过绿色荧光标记,适合长期细胞追踪和体内成像研究。
Sakamoto, K., et al. (2020) Efficient tissue-type specific expression of target genes in a tetracycline-controlled manner from the ubiquitously active Eef1a1 locus. Sci Rep 10, 207. https://doi.org/10.1038/s41598-019-57052-z